2-Oxa-6-azaspiro[3.3]heptane → (6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-yl)-(2-oxa-6-aza-spiro[3.3]hept-6-yl)-methanone

HRID 168369Notes

Reaction equation

HRID 168369 reaction equation
[CH2:20]1[O:21][CH2:22][C:23]12[CH2:24][NH:25][CH2:26]2.[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][CH2:17][CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][CH2:17][CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[N:25]3[CH2:24][C:23]4([CH2:20][O:21][CH2:22]4)[CH2:26]3)[n:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 231118872-Oxa-6-azaspiro[3.3]heptaneHCID 710877336-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid

Product 1

HCID 71087919(6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-yl)-(2-oxa-6-aza-spiro[3.3]hept-6-yl)-methanone

Sources & evidence

ORD record
ord-8677a7e8662b4cafa28d18b807cc044b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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