HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → 2-(2-Hydroxyethylamino)-1-phenacylbenzimidazole dihydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | 2-((1H-1,3-benzodiazol-2-yl)amino)ethan-1-ol | HCID 583867 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 2-(2-Hydroxyethylamino)-1-phenacylbenzimidazole dihydrobromide | HCID 19040800 | 89% |
Reaction Steps
Heat at reflux for three hours 8.95 g (50 mmol) of 2-(2-hydroxyethylamino)benzimidazole and 10 g of phenacyl bromide in 100 ml of 2-propanol. Allow to cool. Suction-filter the resulting precipitate and wash with acetone. The title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05639756 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-56f1251b0bfe48a1a10d1bc1a6ff7a9f |
| Source note | uspto-grants-1997_06 |