Acetone → 2-Amino-4-(4-chlorophenacyl)-1-(2-morpholinoethyl)benzimidazolium bromide

Participants

Reaction Steps

A solution of 2.33 g (10 mmol) of 4-chlorophenyl bromide in 25 ml of acetone is added to a hot solution of 2-amino-1-(2-morpholinoethyl)benzimidazole (2.46 g, 10 mmol) in 75 ml of acetone. The mixture is stirred, heated at the boil for 5 minutes and maintained at room temperature. Three hours later a precipitate of the title compound appears, which is filtered and washed with acetone and with ether.

Provenance & Evidence