HCID 54448452, compound → HCID 19040674, compound

Participants

Reaction Steps

A solution of 5-(9-chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepin-6-yl)-2,4-pentadienal (3 g) in ethanol (100 ml) and platinum oxide was shaken under hydrogen (50 psi) for 2 hours, filtered, concentrated and the residue chromatographed on silica gel eluted with a gradient of methanol-methylene chloride (3:97°-7:93) to give 0.5 g of 9-chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine-6-pentanal.

Provenance & Evidence