3,4-Diethoxybenzene-1-carbothioamide → HCID 19041009, compound

HRID 1683781Notes

Reaction equation

HRID 1683781 reaction equation
C([O:3][C:4]([C:6]1[NH:10][C:9]([C:11](=O)[CH2:12]Br)=[N:8][CH:7]=1)=[O:5])C.[CH2:15]([O:17][C:18]1[CH:19]=[C:20]([CH:24]=[CH:25][C:26]=1[O:27][CH2:28][CH3:29])[C:21]([NH2:23])=[S:22])[CH3:16]>>[CH2:15]([O:17][C:18]1[CH:19]=[C:20]([C:21]2[S:22][CH:12]=[C:11]([C:9]3[NH:10][C:6]([C:4]([OH:3])=[O:5])=[CH:7][N:8]=3)[N:23]=2)[CH:24]=[CH:25][C:26]=1[O:27][CH2:28][CH3:29])[CH3:16]

Participants

3

Reactant 2

HCID 77452503,4-Diethoxybenzene-1-carbothioamideHCID 19041091HCID 19041091, compound

Product 1

HCID 19041009HCID 19041009, compound

Procedure

A reaction was conducted in the same manner as in Example 1, by using 5-ethoxycarbonyl-2-(α-bromoacetyl)imidazole and 3,4-diethoxythiobenzamide. Then, hydrolysis was conducted in the same manner as in Example 2 to obtain 2-(3,4-diethoxyphenyl)-4-(5-carboxy-2-imidazolyl)thiazole.

Workup

  1. customThen, hydrolysis

Sources & evidence

ORD record
ord-c2bd68647f4a462b880792054c7ca91b
Source dataset
uspto-grants-1997_06
Patent number
US05639770

Reaction notes

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