3,4-Diethoxybenzene-1-carbothioamide → HCID 19041045, compound

HRID 1683788Notes

Reaction equation

HRID 1683788 reaction equation
[C:1]([CH:4]1[CH2:8][CH2:7][CH2:6][N:5]1[C:9]1[N:14]=[C:13]([C:15](=O)[CH2:16]Br)[CH:12]=[CH:11][CH:10]=1)([OH:3])=[O:2].[CH2:19]([O:21][C:22]1[CH:23]=[C:24]([CH:28]=[CH:29][C:30]=1[O:31][CH2:32][CH3:33])[C:25]([NH2:27])=[S:26])[CH3:20]>>[CH2:19]([O:21][C:22]1[CH:23]=[C:24]([C:25]2[S:26][CH:16]=[C:15]([C:13]3[CH:12]=[CH:11][CH:10]=[C:9]([N:5]4[CH2:6][CH2:7][CH2:8][CH:4]4[C:1]([OH:3])=[O:2])[N:14]=3)[N:27]=2)[CH:28]=[CH:29][C:30]=1[O:31][CH2:32][CH3:33])[CH3:20]

Participants

3

Reactant 2

HCID 77452503,4-Diethoxybenzene-1-carbothioamideHCID 19041073HCID 19041073, compound

Product 1

HCID 19041045HCID 19041045, compound

Procedure

A reaction was conducted in the same manner as in Example 1, by using 6-(2-carboxy-1-pyrrolidinyl)-2-(α-bromoacetyl)pyridine and 3,4-diethoxythiobenzamide, to obtain 2-(3,4-diethoxyphenyl)-4-[6-(2-carboxy-1-pyrrolidinyl)-2-pyridyl]thiazole.

Sources & evidence

ORD record
ord-cdcd3da0c15c4bf58077007d122c9622
Source dataset
uspto-grants-1997_06
Patent number
US05639770

Reaction notes

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