3,4-Diethoxybenzene-1-carbothioamide → HCID 19041031, compound

HRID 1683792Notes

Reaction equation

HRID 1683792 reaction equation
[C:1]1([CH:7]([C:9]2[N:14]=[C:13]([C:15](=O)[CH2:16]Br)[CH:12]=[CH:11][CH:10]=2)[OH:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:19]([O:21][C:22]1[CH:23]=[C:24]([CH:28]=[CH:29][C:30]=1[O:31][CH2:32][CH3:33])[C:25]([NH2:27])=[S:26])[CH3:20]>>[CH2:19]([O:21][C:22]1[CH:23]=[C:24]([C:25]2[S:26][CH:16]=[C:15]([C:13]3[CH:12]=[CH:11][CH:10]=[C:9]([CH:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[OH:8])[N:14]=3)[N:27]=2)[CH:28]=[CH:29][C:30]=1[O:31][CH2:32][CH3:33])[CH3:20]

Participants

3

Reactant 2

HCID 77452503,4-Diethoxybenzene-1-carbothioamideHCID 19041103HCID 19041103, compound

Product 1

HCID 19041031HCID 19041031, compound

Procedure

A reaction was conducted in the same manner as in Example 1, by using 6-(1-phenyl-1-hydroxymethyl)-2-(α-bromoacetyl)pyridine and 3,4-diethoxythiobenzamide, to obtain 2-(3,4-diethoxyphenyl)-4-[6-(1-phenyl-1-hydroxymethyl)-2-pyridyl]thiazole.

Sources & evidence

ORD record
ord-40f1c27e6e2b4ad99a2cba0068c82e2f
Source dataset
uspto-grants-1997_06
Patent number
US05639770

Reaction notes

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