3,4-Diethoxybenzene-1-carbothioamide → HCID 19041135, compound

HRID 1683794Notes

Reaction equation

HRID 1683794 reaction equation
[C:1]([CH:4]([C:6]1[N:11]=[C:10]([C:12](=O)[CH2:13]Br)[CH:9]=[CH:8][CH:7]=1)[OH:5])([OH:3])=[O:2].[CH2:16]([O:18][C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][C:27]=1[O:28][CH2:29][CH3:30])[C:22]([NH2:24])=[S:23])[CH3:17]>>[CH2:16]([O:18][C:19]1[CH:20]=[C:21]([C:22]2[S:23][CH:13]=[C:12]([C:10]3[CH:9]=[CH:8][CH:7]=[C:6]([CH:4]([C:1]([OH:3])=[O:2])[OH:5])[N:11]=3)[N:24]=2)[CH:25]=[CH:26][C:27]=1[O:28][CH2:29][CH3:30])[CH3:17]

Participants

3

Reactant 2

HCID 77452503,4-Diethoxybenzene-1-carbothioamideHCID 19041051HCID 19041051, compound

Product 1

HCID 19041135HCID 19041135, compound

Procedure

A reaction was conducted in the same manner as in Example 1, by using 6-(1-carboxy-1-hydroxymethyl)-2-(α-bromoacetyl)pyridine and 3,4-diethoxythiobenzamide, to obtain 2-(3,4-diethoxyphenyl)-4-[6-(1-carboxy-1-hydroxymethyl)-2-pyridyl]thiazole

Sources & evidence

ORD record
ord-7e56d52b678a4fa68257624099ed6e37
Source dataset
uspto-grants-1997_06
Patent number
US05639770

Reaction notes

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