HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1683798Generated: November 2, 2026
Methyl cyanoacetate → HCID 19041044, compound
https://huagongshe.com/reaction/1683798
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl cyanoacetate | HCID 7747 | — |
| Reactant | HCID 19041120 | HCID 19041120 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | HCID 19041044 | HCID 19041044 | 56.6% |
Reaction Steps
A mixture of 3 g of 2-[2-(3,4-diethoxyphenyl)-4-thiazolyl]pyridine-1-oxide, 2.6 g of methyl cyanoacetate and 150 ml of acetic anhydride was stirred at 110° C. for 4 hours and then allowed to cool. The resulting crystals were collected by filtration and recrystallized from ethanol-dimethylformamide to obtain 2.1 g of 2-(3,4-diethoxyphenyl)-4-[6-(1-methoxycarbonyl-1-cyanomethyl)-2-pyridyl]thiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05639770 |
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| Source dataset | uspto-grants-1997_06 |
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| ORD ID | ord-5a5b9f4cc2704f3a9e8bbd57e371a208 |
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| Source note | uspto-grants-1997_06 |
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