Lawesson's reagent → HCID 86750965, compound

Participants

Reaction Steps

A mixture of 1.0 g (3.8 mmol) of 3-(4-chlorophenyl)-1-propyl-4, 5-dihydropyrazol-5-one, 1.2 g (3.0 mmol) of Lawesson's reagent, and 10 ml of toluene was heated under reflux for 2 hours. The reaction solution was concentrated and the residue was purified by silica gel column chromatography (n-hexane/ethyl acetate=10/1 (v/v)) to give 1.0 g of the object compound as a yellow oil (yield 94%).

Provenance & Evidence