Water → HCID 10537561, compound

Participants

Reaction Steps

A solution of N-(5-amino-indan-2-yl)-N-propylpropionamide (2.6 g, 10.5 mmol) in dry diethyl ether (50 mL) was added to a slurry of lithiumaluminum hydride (1.0 g, 26 mmol) in diethyl ether (150 mL) at ambient temperature. After stirring for 1.5 hours water (1.0 mL) followed by 15% sodium hydroxide (1.0 mL) and water (3.0 mL). After stirring for 10 minutes, the inorganic material was filtered off and the resulting solution was evaporated to yield 2.2 g (90%) of the desired product as an oil.:

Provenance & Evidence