HCID 19041500, compound → HCID 19041587, compound

Participants

Reaction Steps

To a stirred solution of 1-[6-(cyclopropylmethyl-propyl-amino)-1,5,6,7-tetrahydro-1-aza-s-indacen-3-yl]-propan-1-one (12h, Chart 2) (58 mg, 0.18 mmol) in dry diethyl ether (4 mL) was added in small portions lithium aluminum hydride (40 mg, 1.06 mmol). The reaction mixture was stirred over night and then quenched by the consecutive addition of water (40 μL), 15% sodium hydroxide (40 μL) and water (120 μL). After stirring for 15 min., the solid material was filtered off and the solvent removed in vacuo to yield a residue of 28 mg (50%) of the title compound.

Provenance & Evidence