HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2,4-Dinitrobenzene → HCID 19040750, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2,4-Dinitrobenzene | HCID 6 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-(2-DIMETHYLAMINO-ETHYL)-1H-INDOL-5-YLAMINE | HCID 11820211 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19040750 | HCID 19040750 | 73% |
Reaction Steps
5-Amino-3-(2-dimethylaminoethyl)indole and 1-chloro-2,4-dinitrobenzene were used. Triethylamine was used as base, tetrahydrofuran was used as solvent, and the reaction was stirred at room temperature for 2 hours. Chromatography afforded the title compound (73%) as a dark red solid: mp, 177.0°-179.0° C.; 13C NMR (DMSO-d6) δ148.2, 135.6, 135.2, 130.1, 129.6, 128.2, 127.9, 124.3, 123.5, 119.6, 116.9. 116.3, 113.3, 112.5, 60.0, 45.2, 23.0; FAB HRMS calculated for C18H19N5O4.[H+ ]370.1517, found 370.1492.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05639752 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-58e01cbe53f84c02bec08db1d9f556ce |
| Source note | uspto-grants-1997_06 |