Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 6-Chloropurine | HCID 5359277 | — |
| Reactant | 3-(2-DIMETHYLAMINO-ETHYL)-1H-INDOL-5-YLAMINE | HCID 11820211 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 19040735 | HCID 19040735 | 66% |
Reaction Steps
5-Amino-3-(2-dimethylaminoethyl)indole and 6-chloropurine were used. No base was used, acetic acid was used as solvent, and the reaction was heated at reflux (116° C.) for 15 hours. Chromatography afforded the title compound (66%) as a white foam: mp, decomposes 175° C.; 13C NMR (CD3OD) δ153.7, 153.4, 141.5, 136.0, 131.5, 128.3, 125.6, 119.2, 113.3, 113.0, 109.9, 59.1, 43.6, 21.9. Anal. calcd for C17H19N7.HCl.2H2O: C, 51.84; H, 6.14; N, 24.89. Found: C, 52.14; H, 6.22; N, 25.03.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05639752 |
|---|
| Source dataset | uspto-grants-1997_06 |
|---|
| ORD ID | ord-bdfce52d3dea453a930f6accfae5d1f6 |
|---|
| Source note | uspto-grants-1997_06 |
|---|
