HuagongsheHuagongshe Chemistry Print Report · For research reference only
[1-(3-Oxobut-1-en-1-yl)cyclopropyl]acetonitrile → [1-(3-Oxobutan-1-yl)cyclopropyl]acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [1-(3-Oxobut-1-en-1-yl)cyclopropyl]acetonitrile | HCID 53970073 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | [1-(3-Oxobutan-1-yl)cyclopropyl]acetonitrile | HCID 19041667 | 101.2% |
Reaction Steps
A solution of the olefin from Step 1 (4.08 g, 26.8 mmol) in 85 mL ethyl acetate was treated with 30 psi hydrogen over 5% palladium on carbon (300 rag) in a Parr shaker for 1.5 h. The mixture was filtered through celite and evaporated to give 4.1 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05639780 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-2694639149ec464c8d04aacd39c273a7 |
| Source note | uspto-grants-1997_06 |