Ammonium Chloride → HCID 19041704, compound

Participants

Reaction Steps

To the product of Step 1 (210 mg, 0.68 mmol) in dry DMF (5 mL) at 0° C. was added Nail (30 mg, 0.74 mmol, 60% in oil) followed by 4-bromobenzyl bromide (174 mg, 0.7 mmol). The mixture was stirred at r.t. for 0.5 h. NH4Cl solution was added. The mixture was extracted with EtOAc. Chromatography of the concentrated organic extract gave 272 mg of the title compound.

Provenance & Evidence