HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethylaniline → Methyl N-(2,6-dimethylphenyl)-DL-alaninate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethylaniline | HCID 6896 | — |
| Reactant | Metalaxyl | HCID 42586 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Alpha-bromopropionate | HCID 14535398 | — |
| Product | Methyl N-(2,6-dimethylphenyl)-DL-alaninate | HCID 94555 | — |
Reaction Steps
The preparation of metalaxyl is published in the CH-PS 607,888, according to which 2,6-dimethylaniline is first reacted with methyl DL-α-bromopropionate in the presence of sodium hydrogen carbonate as acid binding agent, then methyl N-(2,6-dimethylphenyl)-DL-alaninate thus obtained is acylated with methoxyacetyl chloride to give metalaxyl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05639905 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-477b7476c77943e99d6ea4ee8b9d3031 |
| Source note | uspto-grants-1997_06 |