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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1684388Generated: October 26, 2026

4-Methylbenzenethiol → 1-[[(4-Methylphenyl)thio]methyl]-4-(trifluoromethoxy)benzene

https://huagongshe.com/reaction/1684388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzenethiolHCID 7811—
Reactant4-(Trifluoromethoxy)benzyl ChlorideHCID 2777261—
Product1-[[(4-Methylphenyl)thio]methyl]-4-(trifluoromethoxy)benzeneHCID 1085161180.1%

Reaction Steps

The procedure of Example 87 is repeated using 11.8 g of p-thiocresol and 9.6 g of 4-(trifluoromethoxy)benzyl chloride. This affords 10.9 g of the desired product as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05639887
Source datasetuspto-grants-1997_06
ORD IDord-db12f1db96d44ce0affa9c32a8e2dfe1
Source noteuspto-grants-1997_06