3-Fluoro-4-(trifluoromethoxy)phenol → HCID 178444225, compound

HRID 1684453Notes

Reaction equation

HRID 1684453 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([OH:13])[CH:5]=[CH:6][C:7]=1[O:8][C:9]([F:12])([F:11])[F:10].Br[CH2:15][CH:16]1[CH2:21][CH2:20][Si:19]([CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])(C2C=CC=CC=2)[CH2:18][CH2:17]1>>[F:1][C:2]1[CH:3]=[C:4]([O:13][CH2:15][C@H:16]2[CH2:21][CH2:20][Si@H:19]([CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH2:18][CH2:17]2)[CH:5]=[CH:6][C:7]=1[O:8][C:9]([F:11])([F:12])[F:10]

Participants

3

Reactant 2

HCID 27833573-Fluoro-4-(trifluoromethoxy)phenolHCID 189357894-Bromomethyl-1-n-heptyl-1-phenyl-1-silacyclohexane

Product 1

HCID 178444225HCID 178444225, compound

Procedure

The general procedure of Example 9 was repeated using 3-fluoro-4-trifluoromethoxyphenol and 4-bromomethyl-1-n-heptyl-1-phenyl-1-silacyclohexane, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-25f89361c2fc4a4baa26aacb8a58a938
Source dataset
uspto-grants-1997_06
Patent number
US05641430

Reaction notes

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