4-(Trifluoromethyl)phenol → HCID 178494952, compound

HRID 1684455Notes

Reaction equation

HRID 1684455 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.Br[CH2:13][Si:14]1(C2C=CC=CC=2)[CH2:19][CH2:18][CH:17]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][O:25][CH3:26])[CH2:16][CH2:15]1>>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[CH:5][C:6]([O:9][CH2:13][Si@H:14]2[CH2:19][CH2:18][C@H:17]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][O:25][CH3:26])[CH2:16][CH2:15]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 678744-(Trifluoromethyl)phenolHCID 19039052HCID 19039052, compound

Product 1

HCID 178494952HCID 178494952, compound

Procedure

The general procedure of Example 9 was repeated using 4-trifluoromethylphenol and 4-bromomethyl-1-(5-methoxypentyl)-4-phenyl-4-silacyclohexane, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-e799df5dab1c421aab919ab2fb287dc2
Source dataset
uspto-grants-1997_06
Patent number
US05641430

Reaction notes

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