3,4-Difluorophenol → HCID 178506031, compound

HRID 1684459Notes

Reaction equation

HRID 1684459 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[CH:6][C:7]=1[F:8].Br[CH2:11][CH:12]1[CH2:17][CH2:16][Si:15]([CH2:24][CH2:25][CH2:26][CH2:27][F:28])(C2C=CC=CC=2)[CH2:14][CH2:13]1>>[F:1][C:2]1[CH:3]=[C:4]([O:9][CH2:11][C@H:12]2[CH2:13][CH2:14][Si@H:15]([CH2:24][CH2:25][CH2:26][CH2:27][F:28])[CH2:16][CH2:17]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 759273,4-DifluorophenolHCID 19039089HCID 19039089, compound

Product 1

HCID 178506031HCID 178506031, compound

Procedure

The general procedure of Example 9 was repeated using 3,4-difluorophenol and 4-bromomethyl-1-(4-fluorobutyl)-1-phenyl-1-silacyclohexane, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-8c988b0d737248b8a6381b3e63dcdaaf
Source dataset
uspto-grants-1997_06
Patent number
US05641430

Reaction notes

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