4-Bromomethyl-1-n-heptyl-1-phenyl-1-silacyclohexane → HCID 178444224, compound

HRID 1684461Notes

Reaction equation

HRID 1684461 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([OH:14])[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][C:10]([F:13])([F:12])[F:11].Br[CH2:16][CH:17]1[CH2:22][CH2:21][Si:20]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])(C2C=CC=CC=2)[CH2:19][CH2:18]1>>[F:1][C:2]1[CH:3]=[C:4]([O:14][CH2:16][C@H:17]2[CH2:22][CH2:21][Si@H:20]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH2:19][CH2:18]2)[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][C:10]([F:12])([F:13])[F:11]

Participants

3

Reactant 2

HCID 189357894-Bromomethyl-1-n-heptyl-1-phenyl-1-silacyclohexaneHCID 190391123-Fluoro-4-(2,2,2-trifluoroethoxy)phenol

Product 1

HCID 178444224HCID 178444224, compound

Procedure

The general procedure of Example 9 was repeated using 3-fluoro-4-(2,2,2-trifluoroethoxy)phenol and 4-bromomethyl-1-n-heptyl-1-phenyl-1-silacyclohexane, thereby obtaining the intended compound.

Workup

  1. customobtaining the intended compound

Sources & evidence

ORD record
ord-9df8e0328673436e84028576003cd260
Source dataset
uspto-grants-1997_06
Patent number
US05641430

Reaction notes

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