4-(Trifluoromethyl)phenol → HCID 178494951, compound

HRID 1684467Notes

Reaction equation

HRID 1684467 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.Br[CH2:13][C@H:14]1[CH2:19][CH2:18][C@H:17]([Si:20]2(C3C=CC=CC=3)[CH2:25][CH2:24][CH:23]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][O:31][CH3:32])[CH2:22][CH2:21]2)[CH2:16][CH2:15]1>>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[CH:5][C:6]([O:9][CH2:13][C@H:14]2[CH2:15][CH2:16][C@H:17]([Si@H:20]3[CH2:25][CH2:24][C@H:23]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][O:31][CH3:32])[CH2:22][CH2:21]3)[CH2:18][CH2:19]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 678744-(Trifluoromethyl)phenolHCID 178494940HCID 178494940, compound

Product 1

HCID 178494951HCID 178494951, compound

Procedure

The general procedure of Example 39 was repeated using 4-trifluoromethylphenol and 4-(trans-4-bromomethylcyclohexyl)-4-phenyl-1-(5-methoxypentyl)-4-silacyclohexane, thereby obtaining the intended product.

Workup

  1. customobtaining the intended product

Sources & evidence

ORD record
ord-f1d628575bff411fb5e2fff4e31e0b01
Source dataset
uspto-grants-1997_06
Patent number
US05641430

Reaction notes

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