4-(Difluoromethoxy)phenol → HCID 178460954, compound

HRID 1684469Notes

Reaction equation

HRID 1684469 reaction equation
[F:1][CH:2]([F:11])[O:3][C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1.Br[CH2:13][CH:14]1[CH2:19][CH2:18][Si:17](C2CCCC[Si]2(C2C=CC=CC=2)CCC)([C:20]2[CH:25]=[CH:24]C=[CH:22][CH:21]=2)[CH2:16][CH2:15]1>>[F:1][CH:2]([F:11])[O:3][C:4]1[CH:5]=[CH:6][C:7]([O:10][CH2:13][C@H:14]2[CH2:15][CH2:16][Si@H:17]([C@H:20]3[CH2:21][CH2:22][Si@H:17]([CH2:16][CH2:15][CH3:14])[CH2:24][CH2:25]3)[CH2:18][CH2:19]2)=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 27741244-(Difluoromethoxy)phenolHCID 53639784HCID 53639784, compound

Product 1

HCID 178460954HCID 178460954, compound

Procedure

The general procedure of Example 39 was repeated using 4-difluoromethoxyphenol and 4-bromomethyl-1-phenyl-1-silacyclohexyl-1-phenyl-1-n-propyl-1-silacyclohexane, thereby obtaining the intended product.

Workup

  1. customobtaining the intended product

Sources & evidence

ORD record
ord-45fe6ca9c3784f049a20ee087e923b69
Source dataset
uspto-grants-1997_06
Patent number
US05641430

Reaction notes

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