3,4,5-Trifluorophenol → HCID 178461115, compound

HRID 1684471Notes

Reaction equation

HRID 1684471 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([OH:10])[CH:5]=[C:6]([F:9])[C:7]=1[F:8].Br[CH2:12][C@H:13]1[CH2:18][CH2:17][C@H:16]([CH:19]2[CH2:24][CH2:23][Si:22](C3C=CC=CC=3)([CH2:25][CH2:26][CH2:27][CH:28]([F:30])[CH3:29])[CH2:21][CH2:20]2)[CH2:15][CH2:14]1>>[F:1][C:2]1[CH:3]=[C:4]([O:10][CH2:12][C@H:13]2[CH2:14][CH2:15][C@H:16]([C@H:19]3[CH2:20][CH2:21][Si@H:22]([CH2:25][CH2:26][CH2:27][CH:28]([F:30])[CH3:29])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[CH:5]=[C:6]([F:9])[C:7]=1[F:8]

Participants

3

Reactant 2

HCID 27779433,4,5-TrifluorophenolHCID 178461113HCID 178461113, compound

Product 1

HCID 178461115HCID 178461115, compound

Procedure

The general procedure of Example 39 was repeated using 3,4,5-trifluorophenol and 4-(trans-4-bromomethylcyclohexyl)-I-phenyl-1-(4-fluoropentyl)-1-silacyclohexane thereby obtaining the intended product.

Workup

  1. customthereby obtaining the intended product

Sources & evidence

ORD record
ord-5af51ba3146d45d2a589a833b6cbe04d
Source dataset
uspto-grants-1997_06
Patent number
US05641430

Reaction notes

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