HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → (8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-(3-phenylpropanoyl)-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 54148895 | HCID 54148895 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-(3-phenylpropanoyl)-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid | HCID 11026423 | — |
Reaction Steps
A mixture of methyl 17β-(phenethylcarbonyl)-androsta-3,5-diene-3-carboxylate, K2CO3, water and methanol is heated at reflux for about 5 hours. Acidification followed by conventional workup yields title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05641765 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-8f4239ecce904ce88bf1ae2b10f896cd |
| Source note | uspto-grants-1997_06 |