HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 54160510, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | (8S,9S,10R,13S,14S,17S)-10,13-dimethyl-17-(3-phenylpropanoyl)-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid | HCID 11026423 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 54160510 | HCID 54160510 | — |
Reaction Steps
Into a 250 mL 3-neck round bottom flask is placed 17β-(phenethylcarbonyl)-androsta-3,5-diene-3-carboxylic acid and an excess of sodium hydroxide. To the flask is added dimethyl sulfoxide as a solvent. The mixture is heated to reflux for 3 hours. Standard workup followed by isolation by preparative HPLC yields title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05641765 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-285726ad206d4758b4ff5452085d0e1f |
| Source note | uspto-grants-1997_06 |