2,4-Nonanedione → 4-(3,4-Dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxy-2-methylquinoline

HRID 1684576Notes

Reaction equation

HRID 1684576 reaction equation
Cl.[NH2:2][C:3]1[CH:20]=[C:19]([O:21][CH3:22])[C:18]([O:23][CH3:24])=[CH:17][C:4]=1[C:5]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[C:9]([O:15][CH3:16])[CH:8]=1)=O.[CH3:25][C:26](=O)[CH2:27][C:28](=[O:34])[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]>>[CH3:16][O:15][C:9]1[CH:8]=[C:7]([C:5]2[C:4]3[C:3](=[CH:20][C:19]([O:21][CH3:22])=[C:18]([O:23][CH3:24])[CH:17]=3)[N:2]=[C:26]([CH3:25])[C:27]=2[C:28](=[O:34])[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH:12]=[CH:11][C:10]=1[O:13][CH3:14]

Participants

3

Reactant 2

HCID 803142,4-NonanedioneHCID 214661342-Amino-3',4',4,5-tetramethoxybenzophenone hydrochloride

Product 1

HCID 190398854-(3,4-Dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxy-2-methylquinoline

Procedure

According to the same manner as that described in Reference Example 6, 2-amino-3',4',4,5-tetramethoxybenzophenone hydrochloride was reacted with 2,4-nonanedione to give 4-(3,4-dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxy-2-methylquinoline. This compound was recrystallized from ethanol to give colorless prisms. mp. 123°-125° C.

Sources & evidence

ORD record
ord-cd97c83fffdf4d66bc6da086a61ca896
Source dataset
uspto-grants-1997_06
Patent number
US05641788

Reaction notes

Loading…