2,4-Heptanedione, 6-methyl- → 4-(3,4-Dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxy-2-methylquinoline

Participants

Role	Name	HCID	Charge
Reactant	2,4-Heptanedione, 6-methyl-	HCID 76354	—
Reactant	2-Amino-3',4',4,5-tetramethoxybenzophenone hydrochloride	HCID 21466134	—
Product	4-(3,4-Dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxy-2-methylquinoline	HCID 19039903	—

Reaction Steps

According to the same manner as that described in Reference Example 6, 2-amino-3',4',4,5-tetramethoxybenzophenone hydrochloride was reacted with 6-methyl-2,4-heptanedione to give 4-(3,4-dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxy-2-methylquinoline. This compound was recrystallized from ethyl acetate-hexane to give colorless prisms. mp. 135°-137° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05641788
Source dataset	uspto-grants-1997_06
ORD ID	ord-ab1656257a47449eb2535eb25de22302
Source note	uspto-grants-1997_06