N-tert-Butylethylamine → 3-acetyl-2-(N-tert-butyl-N-ethylaminomethyl)-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline

Participants

Role	Name	HCID	Charge
Reactant	N-tert-Butylethylamine	HCID 521156	—
Reactant	3-Acetyl-2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline	HCID 19039905	—
Product	3-acetyl-2-(N-tert-butyl-N-ethylaminomethyl)-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline	HCID 19039892	—

Reaction Steps

According to the same manner as that described in Example 1, 3-acetyl-2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline was reacted with N-tert-butyl-N-ethylamine to give 3-acetyl-2-(N-tert-butyl-N-ethylaminomethyl)-4-(3,4-dimethoxyphenyl)-6,7-dimethoxyquinoline. This compound was recrystallized from methanol to give colorless prisms. mp. 156°-157° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05641788
Source dataset	uspto-grants-1997_06
ORD ID	ord-447b0500dc8041a6b7c2679632aa0387
Source note	uspto-grants-1997_06