HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-tert-Butylethylamine → 4-(3,4-dimethoxyphenyl)-2-(N-tert-butyl-N-ethylaminomethyl)-6,7-dimethoxy-3-valerylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-tert-Butylethylamine | HCID 521156 | — |
| Reactant | 2-Bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-valerylquinoline | HCID 19039881 | — |
| Product | 4-(3,4-dimethoxyphenyl)-2-(N-tert-butyl-N-ethylaminomethyl)-6,7-dimethoxy-3-valerylquinoline | HCID 19039890 | — |
Reaction Steps
According to the same manner as that described in Example 1, 2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-valerylquinoline was reacted with N-tert-butyl-N-ethylamine to give 4-(3,4-dimethoxyphenyl)-2-(N-tert-butyl-N-ethylaminomethyl)-6,7-dimethoxy-3-valerylquinoline. This compound was recrystallized from ethyl acetate-hexane to give colorless prisms. mp. 137°-139° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05641788 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-2ea2ba61468542fb85ecf0e13ecc5cb5 |
| Source note | uspto-grants-1997_06 |