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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1684592Generated: November 1, 2026

Morpholine → 4-(3,4-Dimethoxyphenyl)-6,7-dimethoxy-2-morpholinomethyl-3-valerylquinoline

https://huagongshe.com/reaction/1684592

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant2-Bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-valerylquinolineHCID 19039881—
Product4-(3,4-Dimethoxyphenyl)-6,7-dimethoxy-2-morpholinomethyl-3-valerylquinolineHCID 19039904—

Reaction Steps

According to the same manner as that described in Example 5, 2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-valerylquinoline was reacted with morpholine to give 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-morpholinomethyl-3-valerylquinoline. This compound was recrystallized from ethyl acetate-hexane to give colorless prisms. mp. 137°-138° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05641788
Source datasetuspto-grants-1997_06
ORD IDord-29ec3d0b90324168b693486de6d68bc8
Source noteuspto-grants-1997_06