Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1684594Generated: November 2, 2026

2-Bromomethyl-4-(3,4-dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxyquinoline → 4-(3,4-Dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxy-2-[(1-methylimidazol-2-yl)thiomethyl]quinoline

https://huagongshe.com/reaction/1684594

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromomethyl-4-(3,4-dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxyquinolineHCID 19039898—
ReactantHCID 178480602HCID 178480602—
Product4-(3,4-Dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxy-2-[(1-methylimidazol-2-yl)thiomethyl]quinolineHCID 19039891—

Reaction Steps

According to the same manner as that described in Example 4, 2-bromomethyl-4-(3,4-dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxyquinoline was reacted with 2-mercapto-1-methylimidazole to give 4-(3,4-dimethoxyphenyl)-3-hexanoyl-6,7-dimethoxy-2-[(1-methylimidazol-2-yl)thiomethyl]quinoline. This compound was recrystallized from ethanol to give colorless prisms. mp. 128°-129° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05641788
Source datasetuspto-grants-1997_06
ORD IDord-620b9ce015eb4d5480e776cabf956ed3
Source noteuspto-grants-1997_06