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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1684596Generated: November 2, 2026

Imidazole → 4-(3,4-Dimethoxyphenyl)-2-(1-imidazolylmethyl)-6,7-dimethoxy-3-valerylquinoline

https://huagongshe.com/reaction/1684596

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
Reactant2-Bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-valerylquinolineHCID 19039881—
Product4-(3,4-Dimethoxyphenyl)-2-(1-imidazolylmethyl)-6,7-dimethoxy-3-valerylquinolineHCID 70195037—

Reaction Steps

According to the same manner as that described in Example 3, 2-bromomethyl-4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-3-valerylquinoline was reacted with imidazole to give 4-(3,4-dimethoxyphenyl)-2-(1-imidazolylmethyl)-6,7-dimethoxy-3-valerylquinoline. This compound was recrystallized from ethanol to give colorless prisms. mp. 156°-157° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05641788
Source datasetuspto-grants-1997_06
ORD IDord-b79b5fd835654ba9905c64ee9a7f1d62
Source noteuspto-grants-1997_06