Diethylamine → 2-(N,N-diethylaminomethyl)-4-(3,4-dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxyquinoline

Participants

Role	Name	HCID	Charge
Reactant	Diethylamine	HCID 8021	—
Reactant	2-Bromomethyl-4-(3,4-dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxyquinoline	HCID 19039900	—
Product	2-(N,N-diethylaminomethyl)-4-(3,4-dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxyquinoline	HCID 54488280	—

Reaction Steps

According to the same manner as that described in Example 1, 2-bromomethyl-4-(3,4-dimethoxyphenyl)-3-isovaleryl-6,7-dimethoxyquinoline was reacted with diethylamine to give 2-(N,N-diethylaminomethyl)-4-(3,4-dimethoxyphenyl) -3-isovaleryl-6,7-dimethoxyquinoline. This compound was recrystallized from ethyl acetate-hexane to give colorless prisms. mp. 153°-154° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05641788
Source dataset	uspto-grants-1997_06
ORD ID	ord-52680c37fcb84f17b9f243b93d524d9b
Source note	uspto-grants-1997_06