Methanol → HCID 53974214, compound

Participants

Reaction Steps

To a stirred solution of 13.5 g (0.053 mole) of 5-methoxy-2-benzyloxyacetophenone in 100 ml absolute methanol at ambient temperature was added 2.84 g (0.053 mole) sodium methoxide. After 20 minutes, 8.0 g (0.053 mole) 3-nitrobenzaldehyde was added and the reaction mixture was stirred at ambient temperature for 18 hours. The resulting precipitate was filtered, washed with absolute methanol and then dried in vacuo to afford 20.2 g (98%) the title product as a solid, mp 108°-110° C. Analysis calculated for C23H19NO3 : C, 70.94; H, 4.92; N, 3.60. Found: C, 71.07; H, 4.47; N, 3.46.

Provenance & Evidence