HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,8-Dibromo-(1,2,4)triazolo(1,5-a)pyrazine → 5-bromo-N-(1-(2-morpholinoethyl)-1H-imidazol-2-yl)-[1,2,4]triazolo[1,5-a]pyrazin-8-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,8-Dibromo-(1,2,4)triazolo(1,5-a)pyrazine | HCID 49758022 | — |
| Reactant | 1-(2-morpholinoethyl)-1H-imidazol-2-amine | HCID 57541343 | — |
| Product | 5-bromo-N-(1-(2-morpholinoethyl)-1H-imidazol-2-yl)-[1,2,4]triazolo[1,5-a]pyrazin-8-amine | HCID 57541303 | — |
Reaction Steps
Prepared using Intermediate 3 and Intermediate 10 in a manner analogous to the procedure of Example 1, Step 1. 1H NMR (400 MHz, CDCl3) 2.55 (brs, 4H), 2.71-2.80 (m, 2H), 3.68-3.83 (m, 4H), 4.15-4.26 (m, 2H), 6.92 (s, H), 7.05 (s, H), 7.71 (s, H), 8.31 (s, H), 8.58 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148369B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-695ac797f72e4ff291d345ce7de9649a |
| Source note | uspto-grants-2012_04 |