Ethanolamine → HCID 23079494, compound

HRID 1684964Notes

Reaction equation

HRID 1684964 reaction equation
[CH2:1]([N:8]1[CH:16]=[N:15][C:14]2[C:9]1=[N:10][C:11](Cl)=[N:12][C:13]=2[NH2:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O.[NH2:20][CH2:21][CH2:22][OH:23]>>[CH2:1]([N:8]1[CH:16]=[N:15][C:14]2[C:9]1=[N:10][C:11]([NH:20][CH2:21][CH2:22][OH:23])=[N:12][C:13]=2[NH2:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 700EthanolamineHCID 962WaterHCID 2764829-Benzyl-2-chloro-9h-purin-6-amine

Product 1

HCID 23079494HCID 23079494, compoundYield 100%

Procedure

9-Benzyl-2-chloroadenine (1.0 g, 3.8 mmol) was stirred in 2-aminoethanol (8 ml) at 110° C. for 4 hours. Water (100 ml) was added to the reaction mixture and the resulting precipitate was filtered to give the captioned compound (1.1 g, 3.8 mmol, yield: 100%) as a white solid.

Workup

  1. filtrationthe resulting precipitate was filtered

Sources & evidence

ORD record
ord-e2134302405a43f8bf5f7c76d3ab8349
Source dataset
uspto-grants-2012_04
Patent number
US08148371B2

Reaction notes

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