HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178450372, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178450373 | HCID 178450373 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 178450372 | HCID 178450372 | 63% |
Reaction Steps
2-Butoxy-8-hydroxy-9-(3-methoxycarbonylbenzyl)adenine (0.10 g, 0.27 mmol) obtained by Example 1 was added to 5% sodium hydroxide solution (10 ml) and the solution was stirred at room temperature for 2 hours. After the reaction mixture was neutralized with concentrated hydrochloric acid, the resulting solid was filtered and washed with methanol to give the captioned compound (0.06 g, 0.17 mmol, yield: 61%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148371B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f871f71c8d39440694da65c9208fd52c |
| Source note | uspto-grants-2012_04 |