HCID 25052051, compound → HCID 86661288, compound

HRID 1685023Notes

Reaction equation

HRID 1685023 reaction equation
Cl[CH2:2][C:3]1[N:4]=[C:5]([NH:8][C:9]([NH:11][CH2:12][C:13]2[CH:18]=[C:17]([F:19])[CH:16]=[C:15]([F:20])[CH:14]=2)=[O:10])[S:6][CH:7]=1.ClC1C=C(C=CC=1Cl)[CH2:25][NH:26]C(NC1SC=C(CNC)N=1)=O>>[F:20][C:15]1[CH:14]=[C:13]([CH:18]=[C:17]([F:19])[CH:16]=1)[CH2:12][NH:11][C:9]([NH:8][C:5]1[S:6][CH:7]=[C:3]([CH2:2][NH:26][CH3:25])[N:4]=1)=[O:10]

Participants

3

Reactant 2

HCID 25052051HCID 25052051, compoundHCID 59570823HCID 59570823, compound

Product 1

HCID 86661288HCID 86661288, compound

Procedure

The title compound was prepared from the above 1-(4-Chloromethyl-thiazol-2-yl)-3-(3,5-difluoro-benzyl)-urea following the procedure described for Intermediate 3.

Sources & evidence

ORD record
ord-42e821533322481cb0a7d50d41e9fc0e
Source dataset
uspto-grants-2012_04
Patent number
US08148380B2

Reaction notes

Loading…