HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate → 1-(4-methoxybutanyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate | HCID 215436 | — |
| Reactant | 1-Bromo-2-methoxybutane | HCID 523983 | — |
| Reactant | 1-(2-methoxyethyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid | HCID 43565393 | — |
| Product | 1-(4-methoxybutanyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid | HCID 58055062 | 41% |
Reaction Steps
Prepared by following the same method as the preparation of Intermediate 42, ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate (280 mg) was reacted with 1-bromo-2-methoxybutane (367 mg) to afford white solid (185 mg, 41%). ESI-MS m/z 227.4 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148380B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-7b621e746c2f4526a3ec19581347a70e |
| Source note | uspto-grants-2012_04 |