HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate → 1-(3-methoxypropyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate | HCID 215436 | — |
| Reactant | 1-Bromo-2-methoxybutane | HCID 523983 | — |
| Product | 1-(3-methoxypropyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid | HCID 60925874 | 12% |
Reaction Steps
Prepared by following the same method as the preparation of intermediate 42: ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate (280 mg) was reacted with 1-bromo-2-methoxybutane (337 mg) to afford white solid (42 mg, 0.20 mmol, 10%). ESI-MS m/z 213.2 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148380B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-3dd88e88dac04e4d8705175df269b046 |
| Source note | uspto-grants-2012_04 |