HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-Benzyl-6-chloro-4-methyl-3-oxo-1,3-dihydropyrazolo[3,4-b]pyridine-2-carboxylic acid hexylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 86628147 | HCID 86628147 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-Benzyl-6-chloro-4-methyl-3-oxo-1,3-dihydropyrazolo[3,4-b]pyridine-2-carboxylic acid hexylamide | HCID 86628155 | — |
Reaction Steps
In analogy to example 2, 50 mg (0.16 mmol) of 6-chloro-4-methyl-3-oxo-1,3-dihydro-pyrazolo[3,4-b]pyridin-2-carboxylic acid hexylamide were reacted with 33 mg (0.19 mmol) of bromomethylbenzene in DMF with triethylamine. Yield: 20 mg (31%), M+H+: 401.16.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148395B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-0f2a12e6fd0d4c52ae769919263c4865 |
| Source note | uspto-grants-2012_04 |