HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → 3-(Octahydro-7-indolizinyl)-1-benzenesulfonyl-7-azaindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | 3-(octahydro-7-indolizinyl)-1H-7-azaindole | HCID 10220415 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(Octahydro-7-indolizinyl)-1-benzenesulfonyl-7-azaindole | HCID 9864733 | — |
Reaction Steps
from 3-(octahydro-7-indolizinyl)-1H-7-azaindole (less polar isomer) (10 mg, 0.0415 mmol), benzenesulfonyl chloride (10 μL, 0.0784 mmol) and 1M NaN(TMS)2 (100 μL, 0.10 mmol) in THF (0.5 mL) at RT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148394B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-528d102ff2104f858132e5f5e834a3c7 |
| Source note | uspto-grants-2012_04 |