2-(Methylamino)ethanol → HCID 410267, compound

HRID 1685309Notes

Reaction equation

HRID 1685309 reaction equation
[CH2:1]([N:3]([CH2:20]C)[CH2:4][C:5]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH2:6][NH2:7])C.CNCCO>>[CH3:20][N:3]([CH3:1])[CH2:4][C:5]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)[CH2:6][NH2:7]

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 59200426N1,N1-diethyl-2,2-diphenylpropane-1,3-diamine

Product 1

HCID 410267HCID 410267, compound

Procedure

The title material was prepared as described for the synthesis of N1,N1-diethyl-2,2-diphenylpropane-1,3-diamine (Example Q) in using 2-(methylamino)ethanol. LC/MS (M+H)+: 255. HPLC ret. time (Condition B): 1.300 min. 1H NMR (400 MHz, CDCl3) δ ppm: 1.98 (6H, s), 3.12 (2H, s), 3.54 (2H, s), 7.19-7.22 (6H, m), 7.28-7.31 (4H, m).

Workup

  1. custom1.300 min

Sources & evidence

ORD record
ord-ce298d1bef95445e92bc3e83cf854e6f
Source dataset
uspto-grants-2012_04
Patent number
US08148400B2

Reaction notes

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