Potassium Carbonate → HCID 67265901, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of (±)-5-(3,5-difluorophenyl)-5-methylimidazolidine-2,4-dione from Step A (6.53 g, 28.9 mmol) in DMF (60 mL) was added potassium carbonate (4.39 g, 31.8 mmol) and 4-methoxybenzyl chloride (3.92 mL, 28.9 mmol). The reaction was stirred at ambient temperature for 16 h and at 50° C. for 1 h and then quenched with H2O (100 mL). The resulting precipitate was filtered and rinsed with water to provide the title compound. MS: m/z=347 (M+1).

Provenance & Evidence