(4-Methoxy-3-methylphenyl)boronic acid → HCID 67292824, compound

HRID 1685449Notes

Reaction equation

HRID 1685449 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][C:4]=1[CH3:12].C([O:16][C@@H:17]1[C@@H:30]([O:31]C(=O)C)[C@H:29]([O:35]C(=O)C)[CH2:28][S:27][C@H:18]1[O:19][C:20]1[CH:21]=[N:22][CH:23]=[C:24](Br)[CH:25]=1)(=O)C>>[O:19]([C:20]1[CH:21]=[N:22][CH:23]=[C:24]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[C:4]([CH3:12])[CH:5]=2)[CH:25]=1)[C@@H:18]1[S:27][CH2:28][C@@H:29]([OH:35])[C@H:30]([OH:31])[C@H:17]1[OH:16]

Participants

3

Reactant 2

HCID 2773487(4-Methoxy-3-methylphenyl)boronic acidHCID 441955025-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside

Product 1

HCID 67292824HCID 67292824, compound

Procedure

By following a procedure analogous to Example 122 starting from 4-methoxy-3-methylphenylboronic acid and 5-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, 5-(4-methoxy-3-methylphenyl)-3-pyridinyl 5-thio-β-D-xylopyranoside is obtained in the form of a white solid (yield=21%).

Sources & evidence

ORD record
ord-a3eabcf5b607447bb9e4e3e51cada0ef
Source dataset
uspto-grants-2012_04
Patent number
US08148407B2

Reaction notes

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