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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 168548Generated: October 25, 2026

1-Ethynylcyclohexanol → 2,2,2-trifluoro-N-(3-(3-((1-hydroxycyclohexyl)ethynyl)phenyl)propyl)acetamide

https://huagongshe.com/reaction/168548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-EthynylcyclohexanolHCID 6525—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantN-(3-(3-bromophenyl)propyl)-2,2,2-trifluoroacetamideHCID 57608389—
Product2,2,2-trifluoro-N-(3-(3-((1-hydroxycyclohexyl)ethynyl)phenyl)propyl)acetamideHCID 86635852—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-1b1282a6a6b04b3eac245ad93cb9bdf0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)