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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1685491Generated: October 26, 2026

3-(Propan-2-yloxy)aniline → 6-Chloro-N-(3-isopropoxyphenyl)pyrazine-2-carboxamide

https://huagongshe.com/reaction/1685491

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Propan-2-yloxy)anilineHCID 573220—
Reactant6-Chloropyrazine-2-carbonyl chlorideHCID 15149671—
SolventDichloromethaneHCID 6344—
Product6-Chloro-N-(3-isopropoxyphenyl)pyrazine-2-carboxamideHCID 84820020—

Reaction Steps

The product from Example 15B was reacted with 3-isopropoxyaniline and TEA in CH2Cl2 as described in Example 15C to afford the title compound. MS (DCI/NH3) m/z 309 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148408B2
Source datasetuspto-grants-2012_04
ORD IDord-860a333af98b4bc79a9ceb813bcd9b00
Source noteuspto-grants-2012_04