HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Alcohol → 2-(benzyloxy)-6-chloropyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Alcohol | HCID 244 | — |
| Reactant | 2,6-Dichloropyrazine | HCID 78504 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-(benzyloxy)-6-chloropyrazine | HCID 11746165 | — |
Reaction Steps
Benzylalcohol (500 μL, 7.83 mmol) and potassium tert-butoxide (222.4 mg, 1.82 mmol) in anhydrous DMSO (1 mL) were reacted with 2,6-dichloropyrazine (149.7 mg, 1.00 mmol) as described in Example 19B to afford the title compound. MS (DCI/NH3) m/z 221 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148408B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-5cb0e00e54de4434a7ead7f80137f639 |
| Source note | uspto-grants-2012_04 |